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Chemistry of Heterocyclic Compounds

, Volume 46, Issue 2, pp 223–231 | Cite as

Synthesis of diarylazolo[a]pyridines from [(Z)-2,4-diaryl-4-oxo-2-butenyl]azolium salts

  • L. M. Potikha
  • A. R. Turelyk
  • V. A. Kovtunenko
  • A. V. Turov
Article

A method for the synthesis of derivatives of [1, 3]thiazolo[3,2-a]pyridines, pyrido[2,1-b][1, 3]benzo-thiazole, [1, 3, 4]thiadiazolo[3,2-a]pyridine, and [1, 2, 4]triazolo[4,3-a]pyridine, which includes base initiated cyclization of quaternary azolium salts, formed by the interaction of (Z)-1,3-diaryl-4-bromo-2-buten-1-ones with 1-alkyl-1H-1,2,4-triazoles, 4-methyl-1,3-thiazole, 1,3-benzothiazole, and N-phenyl-1,3,4-thiadiazole-2-amine. Derivatives of 2-chloroimidazo[1,2-a]pyridine were obtained when 5-chloro-1-methyl-1H-imidazole was used.

Keywords

γ-bromodypnone imidazo[1,2-a]pyridine pyrido[2,1-b][1, 3]benzothiazole [1, 3, 4]thiadia-zolo[3,2-a]pyridine [1, 3]thiazolo[3,2-a]pyridine [1, 2, 4]triazolo[4,3-a]pyridine cyclization of azolium ylides 

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Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • L. M. Potikha
    • 1
  • A. R. Turelyk
    • 1
  • V. A. Kovtunenko
    • 1
  • A. V. Turov
    • 1
  1. 1.Taras Shevchenko Kiev National UniversityKievUkraine

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