The corresponding 6-chlorosulfonylquinazoline-2,4-diones were synthesized by the reactions of 1-methylquinazoline-2,4-dione and its 3-alkyl-substituted derivatives with chlorosulfonic acid. Treatment of the products with nucleophilic agents (water or ammonia, aliphatic and cyclic amines) gave 2,4-dioxoquinazolin-6-sulfonic acids or their amides.
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For Communication 1 see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, 1870-1877, December, 2009.
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Kuryazov, R.S., Mukhamedov, N.S. & Shakhidoyatov, K.M. Quinazolines. 2*. unsymmetric 1,3-dialkyl-6-chlorosulfonyl- quinazoline-2,4-diones in nucleo- philic substitution reactions. Chem Heterocycl Comp 45, 1508–1514 (2009). https://doi.org/10.1007/s10593-010-0458-5
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DOI: https://doi.org/10.1007/s10593-010-0458-5