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Synthesis of 7-(4-piperidyl)- [1,6]naphthyridin-5-one and 3-(4-piperidyl)isoqunolin-1-one

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Chemistry of Heterocyclic Compounds Aims and scope

7-(4-Piperidyl)[1,6]napththiridin-5-one was synthesized on the basis of 2-methylnicotinic acid. 3-(4-Piperidyl)isoquinolin-1-one was synthesized from the diethylamide of o-toluic acid and Weinreb's amide of N-Boc-isonipecotic acid.

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References

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Correspondence to D. A. Kovalskiy.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, 1864-1869, December, 2009.

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Kovalskiy, D.A., Perevalov, V.P. Synthesis of 7-(4-piperidyl)- [1,6]naphthyridin-5-one and 3-(4-piperidyl)isoqunolin-1-one. Chem Heterocycl Comp 45, 1503–1507 (2009). https://doi.org/10.1007/s10593-010-0457-6

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  • DOI: https://doi.org/10.1007/s10593-010-0457-6

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