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Chemistry of Heterocyclic Compounds

, Volume 45, Issue 12, pp 1473–1477 | Cite as

Properties of 3,3-dialkyl-3,4-dihydro-isoquinoline cyclic azomethines

  • O. V. Surikov
  • A. G. Mikhailovskii
  • M. I. Vakhrin
Article

The reactions of 3,3-dialkyl-3,4-dihydroisoquinoline cyclic azomethines with the methyl ester and p-toluidide of iodoacetic acid gave stable quaternary ammonium salts which were suitable dipoles for [3+2] cycloaddition reactions. Azomethines activated by iodomethylation react with potassium cyanide and malonodinitrile.

Keywords

3,3-dialkyl-3,4-dihydroisoquinolines methyl ester and p-toluidide of iodoacetic acid quaternary ammonium salts dipolar [3+2] cycloaddition reaction with potassium cyanide and malonodinitrile 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • O. V. Surikov
    • 1
  • A. G. Mikhailovskii
    • 1
  • M. I. Vakhrin
    • 1
  1. 1.Perm State Pharmaceutical AcademyPermRussia

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