Advertisement

Chemistry of Heterocyclic Compounds

, Volume 45, Issue 10, pp 1257–1260 | Cite as

Preparation of aminotriazole-thione derivatives from n-aryl-n-carboxyethyl-β-alanines

  • I. Tumosienė
  • Z. J. Beresnevičius
Article

Depending on the substituents in the aryl moiety, the fusion of N-aryl-N-ethoxycarbonyl-β-alanines with thiocarbohydrazide gives di- or monotriazole derivatives, namely, 4-amino-(2-{[2-(4-amino-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)ethyl]anilino}ethyl)-4,5-dihydro-1H-1,2,4-triazole-5-thiones, 1-[2-(4-amino- 5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)ethyl]-2,3-dihydroquinolin-4(1H)-ones, 4-amino-3-[2-(4-methylanilino))ethyl]-4,5-dihydro-1H-1,2,4-triazole-5-thione and 4-amino-3-[2-(4-ethoxyanilino)-ethyl]-4,5-dihydro-1H-1,2,4-triazole-5-thione. A ditriazolethione derivative was also obtained from the diethyl ester of N-ethoxycarbonyl-N-(4-ethoxyphenyl)- β-alanine.

Keywords

dihydroxyquinolone carboxyalanine triazole cyclization 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    J. Tumosene and Z. I. Bersnevičius, Khim. Geterotsikl. Soedin., 1353 (2007) [Chem. Heterocycl. Comp., 43, 1148 (2007)].Google Scholar
  2. 2.
    G. Mekuskiene, S. Tumkevičius, and P. Vainilavičius, J. Chem. Res. (S), 213 (2002).Google Scholar
  3. 3.
    G. Mekuskiene, and P. Vainilavičius, Khim. Geterotsikl. Soedin., 1088 (2007). [Chem. Heterocycl. Comp., 43, 919 (2007)].Google Scholar
  4. 4.
    K. Kantminene, Dis. Doc. Chem. Sci., Kaunas (1998).Google Scholar
  5. 5.
    N. Demirbas, A. Demirbas, S. A. Karaoglu, and E. Êelik, ARKIVOC, (i), 75 (2005).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  1. 1.Kaunas University of TechnologKaunasLithuania

Personalised recommendations