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Cyclothiomethylation of primary amines with formaldehyde and hydrogen sulfide to nitrogen- and sulfur-containing heterocycles (review)

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Chemistry of Heterocyclic Compounds Aims and scope

Published data and the authors' own experimental results on the synthesis of nitrogen- and sulfur-containing heterocycles based on the cyclothiomethylation of amines with formaldehyde and H2S are reviewed. Features of the three-component condensation are discussed in relation to the nature and structure of the initial amines and also the reaction conditions.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa, 450075, Russia

    V. R. Akhmetova, G. R. Nadyrgulova, Z. T. Niatshina & U. M. Dzhemilev

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  1. V. R. Akhmetova
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  2. G. R. Nadyrgulova
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  3. Z. T. Niatshina
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  4. U. M. Dzhemilev
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Correspondence to V. R. Akhmetova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1443-1469, October, 2009.

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Akhmetova, V.R., Nadyrgulova, G.R., Niatshina, Z.T. et al. Cyclothiomethylation of primary amines with formaldehyde and hydrogen sulfide to nitrogen- and sulfur-containing heterocycles (review). Chem Heterocycl Comp 45, 1155–1176 (2009). https://doi.org/10.1007/s10593-010-0403-7

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