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Synthesis and crystal structure of β-N-(5-methyl-4-oxo-5,6-dihydro-4H-1,3-thiazin-2-yl)isonicotinohydrazide

  • I. V. KulakovEmail author
  • D. M. Turdybekov
  • O. A. Nurkenov
  • G. M. Issabaeva
  • A. S. Makhmutova
  • K. M. Turdybekov
  • S. D. Fazylov
Article

In the presence of amines under mild conditions, β-N-(methacryloylcarbamoythioyl)isonicotinohydrazide underwent intramolecular heterocyclization to give β-N-(5-methyl-4-oxo-5,6-dihydro-4H-1,3-thiazin-2-yl)isonicotinohydrazide, the spatial structure was confirmed by X-ray crystallography.

Keywords

methacryloylthiosemicarbazide of isonicotinic acid intramolecular heterocyclization X-ray crystallography 

References

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    I. V. Kulakov, Khim. Geterotsikl. Soedin., 1104 (2008). [Chem. Heterocycl. Comp., 44, 889 (2008)].Google Scholar
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    G. M. Sheldrick, SHELXL-97 – Crystal Structure Refinement – dos/win95/nt version + 1993-97, Release 97-2.Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • I. V. Kulakov
    • 1
    Email author
  • D. M. Turdybekov
    • 2
  • O. A. Nurkenov
    • 1
  • G. M. Issabaeva
    • 1
  • A. S. Makhmutova
    • 2
  • K. M. Turdybekov
    • 2
  • S. D. Fazylov
    • 1
  1. 1.Institute of Organic Synthesis and Coal Chemistry of Kazakhstan RepublicKaragandaRepublic of Kazakhstan
  2. 2.Research and Production Center ˵Phytochemistry˶Ministry of Education and Science of the Republic of KazakhstanKaragandaRepublic of Kazakhstan

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