Skip to main content
Log in

Synthesis of novel 1,2-functionally-substituted 6,7-dimethoxy-4-spirocyclo-pentanetetrahydroisoquinolines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

1-[(3,4-Dimethoxyphenyl)cyclopentyl]methylamine has been used in the synthesis of 6,7-dimethoxy-4-spirocyclopentane-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid N-methylamide which is employed in the preparation of novel derivatives with substituents in positions 1,2,6, and 7.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. B. Merck, Liebigs Ann. Chem., 66, 125 (1848).

    Google Scholar 

  2. G. L. Grunewald, F. A. Romero, and K. R. Griscione, J. Med. Chem., 48, 134 (2005).

    Article  CAS  Google Scholar 

  3. N. De la Figuera, S. Fiol, J.-C. Fernandez, P. Forns, D. F. Fernez, and F. Alberio, Synth. Lett., 1903 (2006).

  4. A. A. Agekyan, L. Sh. Pirdzhanov, and E. A. Markaryan, Arm. Khim. Zh., 37, 503 (1984).

    CAS  Google Scholar 

  5. G. K. Airapetyan, Zh. S. Arustamyan, R. E. Markaryan, E. M. Arzanunts, L. M. Sarkisyan, A. V. Pogosyan, and E. A. Markaryan, Khim.-Farm. Zh., 24, No. 5, 33 (1990).

    CAS  Google Scholar 

  6. A. L. Mndzhoyan, E. A. Markaryan, Zh. S. Arustamyan, and E. S. Marashyan, Khim. Geterotsikl. Soedin., 637 (1971). [Chem. Heterocycl. Comp., 7, 596 (1971)].

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. A. Aghekyan.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1338–1344, September, 2009.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aghekyan, A.A., Arakelyan, E.A., Panosyan, G.A. et al. Synthesis of novel 1,2-functionally-substituted 6,7-dimethoxy-4-spirocyclo-pentanetetrahydroisoquinolines. Chem Heterocycl Comp 45, 1069–1074 (2009). https://doi.org/10.1007/s10593-009-0385-5

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10593-009-0385-5

Keywords

Navigation