Skip to main content
Log in

Studies on the synthesis of furobenzisoxazole derivatives

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

The present investigation reports the synthesis of new furobenzisoxazole derivatives. Posner reaction of hydroxyfurocoumarin has been studied, wherein the two reaction products are identified as 5-methylfuro[2′,3′:4,5]benzo[1,2-d]isoxazol-3-yl)acetic acid and 1-(6-hydroxy-3-methylbenzofuran-5-yl)ethanone oxime, depending on the conditions used. 1,3,4-Oxadiazole, 2-mercapto-1,3,4-oxadiazole and thiazolidinone derivatives of furobenzisoxazole were synthesized from hydrazide.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Y. Masuda, M. Ishizaki, and M. Shimizu, CNS Drug Rev., 4, 341 (1998).

    CAS  Google Scholar 

  2. U. Hitoshi, M. Kurokawa, Y. Masuda, and H. Nishimura, US Pat. 4172896 (1979); Chem. Abstr., 92, 181160v (1979).

  3. M. Giannella, F. Gualtieri, and M. L. Stein, Phytochemistry, 10, 539 (1971).

    Article  CAS  Google Scholar 

  4. H. Uno, M. Kurokawa, Y. Masuda, and H. Nishimura, J. Med. Chem., 22, 180 (1979).

    Article  CAS  Google Scholar 

  5. M. Jain and C. H. Kwon, J. Med. Chem., 46, 5428 (2003).

    Article  CAS  Google Scholar 

  6. R. Sutherland, E. A. P. Croydon, and G. N. Rolinson, Brit. Med. J., 4, 455 (1970).

    Article  CAS  Google Scholar 

  7. H. Sato, H. Koga, T. Dan, and E. Onuma, US Pat. 4791209 (1988); Chem. Abstr., 106, 196436w (1987).

  8. K. F. Anthony and J. Plattner, US Pat. 4456612 (1984); Chem. Abstr., 101, 171237r (1984).

  9. G. Casini, F. Gualtieri, and M. L. Stein, Phytochemistry, 2, 385 (1965).

    CAS  Google Scholar 

  10. G. Casini, F. Gualtieri, and M. L. Stein, J. Heterocycl. Chem., 6, 279 (1969).

    Article  CAS  Google Scholar 

  11. M. Ginnella, F. Gualtieri, and M. L. Stein, J. Heterocycl. Chem., 8, 397 (1971).

    Article  Google Scholar 

  12. H. Uno, M. Kurokawa, K. Natsuka, Y. Yamato, and H. Nishimura, Chem. Pharm. Bull., 24, 632 (1976).

    CAS  Google Scholar 

  13. J. M. Patel and S. S. Soman, J. Heterocycl. Chem., 44, 945 (2007).

    Article  CAS  Google Scholar 

  14. J. Boyd and A. Robertson, J. Chem. Soc., 174 (1948).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. S. Soman.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1352–1360, September, 2009.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Patel, J.M., Soman, S.S. Studies on the synthesis of furobenzisoxazole derivatives. Chem Heterocycl Comp 45, 1081–1088 (2009). https://doi.org/10.1007/s10593-009-0383-7

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10593-009-0383-7

Keywords

Navigation