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Synthesis of 3-(3-piperidyl)-isoquinoline and 3-(4-piperidyl)-isoquinoline

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Chemistry of Heterocyclic Compounds Aims and scope

3-(3-Piperidyl)isoquinoline and 3-(4-piperidyl)isoquinoline have been synthesized from o-tolylaldehyde aldimines and the methylmethoxycarboxamides (Weinreb amides) of N-Boc-substituted nipecotic and isonipecotic acids.

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Authors and Affiliations

  1. ASINEX Ltd, Moscow, 125480, Russia

    D. A. Kovalskiy

  2. D. I. Mendeleev University of Chemical Technology of Russia, Moscow, 125047, Russia

    V. P. Perevalov

Authors
  1. D. A. Kovalskiy
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  2. V. P. Perevalov
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Correspondence to D. A. Kovalskiy.

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Kovalskiy, D.A., Perevalov, V.P. Synthesis of 3-(3-piperidyl)-isoquinoline and 3-(4-piperidyl)-isoquinoline. Chem Heterocycl Comp 45, 957–964 (2009). https://doi.org/10.1007/s10593-009-0368-6

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  • DOI: https://doi.org/10.1007/s10593-009-0368-6

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