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Synthesis and properties of 4-chloromethyl-6-hydroxy-coumarins and 4-(2-benzofuryl)-6-hydroxycoumarins

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Chemistry of Heterocyclic Compounds Aims and scope

New 4-chloromethyl-6-hydroxycoumarins have been obtained by the condensation of hydroquinone derivatives with 4-chloroacetoacetic ester, and have been used for the synthesis of 4-(2-benzofuryl)-6-hydroxycoumarins. Alkylation and acylation of the phenolic hydroxyl of the synthesized 4-(2-benzo-furyl)coumarins have been investigated.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, Kiev, 02094, Ukraine

    M. S. Frasinyuk

  2. Taras Shevchenko Kiev National University, Kiev, 01033, Ukraine

    S. P. Bondarenko & V. P. Khilya

Authors
  1. M. S. Frasinyuk
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  2. S. P. Bondarenko
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  3. V. P. Khilya
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Correspondence to M. S. Frasinyuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 361–369, March, 2009.

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Frasinyuk, M.S., Bondarenko, S.P. & Khilya, V.P. Synthesis and properties of 4-chloromethyl-6-hydroxy-coumarins and 4-(2-benzofuryl)-6-hydroxycoumarins. Chem Heterocycl Comp 45, 290–296 (2009). https://doi.org/10.1007/s10593-009-0275-x

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  • DOI: https://doi.org/10.1007/s10593-009-0275-x

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