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Chemistry of Heterocyclic Compounds

, Volume 45, Issue 3, pp 290–296 | Cite as

Synthesis and properties of 4-chloromethyl-6-hydroxy-coumarins and 4-(2-benzofuryl)-6-hydroxycoumarins

  • M. S. FrasinyukEmail author
  • S. P. Bondarenko
  • V. P. Khilya
Article

New 4-chloromethyl-6-hydroxycoumarins have been obtained by the condensation of hydroquinone derivatives with 4-chloroacetoacetic ester, and have been used for the synthesis of 4-(2-benzofuryl)-6-hydroxycoumarins. Alkylation and acylation of the phenolic hydroxyl of the synthesized 4-(2-benzo-furyl)coumarins have been investigated.

Keywords

4-(2-benzofuryl)coumarins 4-chloromethylcoumarins alkylation acylation hetero-cyclization 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • M. S. Frasinyuk
    • 1
    Email author
  • S. P. Bondarenko
    • 2
  • V. P. Khilya
    • 2
  1. 1.Institute of Bioorganic Chemistry and PetrochemistryNational Academy of Science of UkraineKievUkraine
  2. 2.Taras Shevchenko Kiev National UniversityKievUkraine

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