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Chemistry of Heterocyclic Compounds

, Volume 45, Issue 3, pp 308–316 | Cite as

Synthesis and oxidation of 2-furyl-4-R-substituted and furo[3,2-c]-condensed 1,2,3,4-tetrahydro-1,10-phenanthrolines and quinolines*

  • V. P. Zaitsev
  • N. M. Mikhailova
  • D. N. Orlova
  • E. V. Nikitina
  • E. V. Boltukhina
  • F. I. ZubkovEmail author
Article

2-Furyl-4-substituted and furo[2,3-c]-condensed 1,2,3,4-tetrahydro-1,10-phenanthrolines were obtained for the first time from 8-aminoquinolines using the Povarov reaction. Various oxidizing agents were shown to effect the elimination of the substituent at C(4) with subsequent aromatization of the tetrahydroquinoline fragment.

Keywords

tetrahydroquinolines 1,10-phenanthrolines oxidation Povarov reaction 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • V. P. Zaitsev
    • 1
  • N. M. Mikhailova
    • 1
  • D. N. Orlova
    • 1
  • E. V. Nikitina
    • 1
  • E. V. Boltukhina
    • 1
  • F. I. Zubkov
    • 1
    Email author
  1. 1.Russian Peoples Friendship UniversityMoscowRussia

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