Chemistry of Heterocyclic Compounds

, Volume 45, Issue 3, pp 341–344 | Cite as

Synthesis of 7- (or 6-)hydroxy derivatives of 3,3-dimethyl-3,4-dihydroisoquinoline

  • Yu. V. ShklyaevEmail author
  • T. S Vshivkova
  • A. G. Tolstikov

When treated with cyanoacetic ester in conc. H2SO4 1-(4-hydroxy-3-methoxyphenyl)- and 1-(3-hydroxy-4-methoxyphenyl)-2-methylpropan-1-ol form ethyl 7-hydroxy-6-methoxy-3,3-dimethyl(or 6-hydroxy-7-methoxy- 3,3-dimethyl)-1,2,3,4-tetrahydroisoquinolylidene-1-acetate.


vanillin 3,3-dimethyldehydrosalsoline 3,3-dimethyldehydroisosalsoline isovanillin 


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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • Yu. V. Shklyaev
    • 1
    Email author
  • T. S Vshivkova
    • 1
  • A. G. Tolstikov
    • 1
  1. 1.Institute of Technical ChemistryUral Branch of the Russian Academy of SciencesPermRussia

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