The reaction of 3-amino-4-(3,4-dimethoxyphenyl)maleimide and the methyl esters of 3-amino-4-(3,4-dimethoxyphenyl)-5-R-thiophene-2-carboxylic acids with carbonyl compounds and nitrous acid has been investigated. Dioxopyrrolo[3,4-c]- and thieno[3,4-c]isoquinolines and cinnolines were obtained.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 449-454, March, 2009.
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Zinchenko, S.Y., Efimenko, R.A., Suikov, S.Y. et al. Acid cyclization of amino-substituted heterocycles. Synthesis of 1,3-dioxo- pyrrolo[3,4-c]- and thieno[3,4-c]isoquino- lines and cinnolines. Chem Heterocycl Comp 45, 365–369 (2009). https://doi.org/10.1007/s10593-009-0262-2
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DOI: https://doi.org/10.1007/s10593-009-0262-2