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Chemistry of Heterocyclic Compounds

, Volume 45, Issue 3, pp 365–369 | Cite as

Acid cyclization of amino-substituted heterocycles. Synthesis of 1,3-dioxo- pyrrolo[3,4-c]- and thieno[3,4-c]isoquino- lines and cinnolines

  • S. Yu. Zinchenko
  • R. A. Efimenko
  • S. Yu. Suikov
  • K. I. Kobrakov
  • S. L. BogzaEmail author
Article

The reaction of 3-amino-4-(3,4-dimethoxyphenyl)maleimide and the methyl esters of 3-amino-4-(3,4-dimethoxyphenyl)-5-R-thiophene-2-carboxylic acids with carbonyl compounds and nitrous acid has been investigated. Dioxopyrrolo[3,4-c]- and thieno[3,4-c]isoquinolines and cinnolines were obtained.

Keywords

aminomaleimide 3-aminothiophene carbonyl compounds cyclization 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • S. Yu. Zinchenko
    • 1
  • R. A. Efimenko
    • 1
  • S. Yu. Suikov
    • 1
  • K. I. Kobrakov
    • 1
  • S. L. Bogza
    • 1
    Email author
  1. 1.L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal ChemistryNational Academy of Sciences of UkraineDonetskUkraine

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