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Chemistry of Heterocyclic Compounds

, Volume 45, Issue 2, pp 201–214 | Cite as

Synthesis of cyclopropyl-substituted 4H-3,1-benzoxazines from 2-amino-phenyl cyclopropyl ketones and 2-cyclopropanoylaminoacylbenzenes

  • S. S. Mochalov
  • M. I. Khasanov
  • N. S. Zefirov
Article

2- and 4-cyclopropyl- and 2,4-dicyclopropyl-substituted 4H-3,1-benzoxazines were synthesized by the intramolecular acid catalyzed heterocyclization of ortho-acylamino-substituted benzyl alcohols, obtained from 2-aminophenyl cyclopropyl ketones and 2-cyclopropanoylaminoacylbenzenes.

Keywords

7-acyl-6-amino-1,4-benzodioxane 4-amino-5-cyclopropanoylveratrole 7-acyl-6-acylamino-1,4-benzodioxanes 2-acylamino-4,5-dimethoxybenzyl alcohols 4-acylamino-5-cyclopropanoylveratroles 2-acylamino-4,5-ethylenedioxybenzyl alcohols 6-cyclopropanoyl-1,4-benzodioxane 4-cyclopropanoyl-veratrole cyclopropyl-substituted 4H-3,1-benzoxazines intramolecular heterocyclization 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • S. S. Mochalov
    • 1
  • M. I. Khasanov
    • 1
  • N. S. Zefirov
    • 1
  1. 1.M. V. Lomonosov Moscow State UniversityMoscowRussia

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