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Synthesis and properties of 2-(2-furyl)benzothiazole

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Chemistry of Heterocyclic Compounds Aims and scope

The electrophilic reactions (nitration, bromination, hydroxymethylation, formylation, acylation) and radical substitution reactions (nitration, arylation) of 2-(2-furyl)benzothiazole have been studied. It was found that all of the reactions occur at position 5 of the furan ring. Only nitration in PPA gave the 5',6-dinitro derivative. Quantum-chemical calculation data for the electron density distribution in the neutral and protonated 2-(2-furyl)benzothiazole molecules are given.

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Authors and Affiliations

  1. South Russia State Technical University, Novocherkassk, 346428, Russia

    E. B. Melnikova & M. M. Elchaninov

  2. South Scientific Centre, Russian Academy of Sciences, Rostov-on-Don, 344006, Russia

    A. A. Milov

  3. Research Institute of Physical and Organic Chemistry, South Federal University, Rostov-on-Don, 344104, Russia

    B. S. Lukyanov

Authors
  1. E. B. Melnikova
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  2. M. M. Elchaninov
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  3. A. A. Milov
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  4. B. S. Lukyanov
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Correspondence to E. B. Melnikova.

Additional information

Dedicated to Boris Aleksandrovich Trofimov on his 70th jubilee.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1331–1338, September, 2008.

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Melnikova, E.B., Elchaninov, M.M., Milov, A.A. et al. Synthesis and properties of 2-(2-furyl)benzothiazole. Chem Heterocycl Comp 44, 1070–1076 (2008). https://doi.org/10.1007/s10593-008-0156-8

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  • DOI: https://doi.org/10.1007/s10593-008-0156-8

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