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Synthesis and reactions of 5-aryl-2-thiophenecarbaldehydes

  • M. D. Obushak
  • V. S. Matiychuk
  • R. Z. Lytvyn
Article

Abstract

The reaction of 2-thiophenecarbaldehyde with arene diazonium chlorides in the presence of CuCl2 catalyst gave 5-aryl-2-thiophenecarbaldehydes. Use of 4-nitrobenzene diazonium chloride in the reaction also gave the isomeric 3-(4-nitrophenyl)-2-thiophenecarbaldehyde. Condensation products of the 5-aryl-2-thiophenecarbaldehydes with cyanoacetic acid esters, cyanoacetamide, and with barbituric and dimethylbarbituric acids were prepared.

Keywords

5-aryl-2-thiophenecarbaldehydes 2-thiophenecarbaldehyde arylation Meerwein reaction 

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Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • M. D. Obushak
    • 1
  • V. S. Matiychuk
    • 1
  • R. Z. Lytvyn
    • 1
  1. 1.Ivano Franko Lviv National UniversityLvivUkraine

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