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Synthesis and stereochemical structure of derivatives of 2-substituted 3-cyclohexenylamidoquinazolin-4-ones obtained from N′-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid and certain orthoesters

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

In the reaction of N′-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid with the trialkyl esters of formic, acetic, valeric, and benzoic acids at room temperature 3-cyclohexenylamidoquinazolin-4-ones with the respective substituent at the C-2 atom of the quinazoline ring were obtained. The spatial structure of the obtained compounds was studied by homonuclear and heteronuclear NMR.

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Authors and Affiliations

  1. Riga Technical University, Riga, LV-1048, Latvia

    D. Zicane, I. Raviņa & Z. Tetere

  2. Latvian Institute of Organic Synthesis, Riga, LV-1006, Latvia

    M. Petrova & E. Liepinsh

Authors
  1. D. Zicane
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  2. I. Raviņa
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  3. Z. Tetere
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  4. M. Petrova
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  5. E. Liepinsh
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Corresponding author

Correspondence to D. Zicane.

Additional information

Translated form Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 899–906, June, 2008.

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Zicane, D., Raviņa, I., Tetere, Z. et al. Synthesis and stereochemical structure of derivatives of 2-substituted 3-cyclohexenylamidoquinazolin-4-ones obtained from N′-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid and certain orthoesters. Chem Heterocycl Comp 44, 722–728 (2008). https://doi.org/10.1007/s10593-008-0104-7

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  • DOI: https://doi.org/10.1007/s10593-008-0104-7

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