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sym-triazines. 8. Synthesis and some reactions of 4,6-disubstituted 2-(1H-pyrrolyl)-1,3,5-triazines

  • A. A. Chesnyuk
  • S. N. Mikhailichenko
  • V. N. Zaplishnyi
  • L. D. Konyushkin
  • S. I. Firgang
Article

Abstract

We have studied the reaction of 2,5-dimethoxytetrahydrofuran with 4,6-disubstituted 2-amino-1,3,5-triazines with the aim of obtaining novel coupled polyheterocyclic systems with potential bioactivity. Reaction conditions were optimized. A series of novel 4,6-disubstituted 2-(1H-1-pyrrolyl)-sym-triazines was obtained. It was found that the product yields depended on the nature of the substituent in the 4 and 6 positions of the triazine ring and on the reaction conditions.

Keywords

4,6-disubstituted 2-amino-1,3,5-triazines 2,5-dimethoxytetrahydrofuran 4-substituted 2-amino-(1,3,5-triazinyl)-6-iminotriphenylphosphoranes 4-substituted 2-(1H-1-pyrrolyl)-6-(1,2,3-triazol-1-yl)-1,3,5-triazines 

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Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • A. A. Chesnyuk
    • 1
  • S. N. Mikhailichenko
    • 2
  • V. N. Zaplishnyi
    • 2
  • L. D. Konyushkin
    • 3
  • S. I. Firgang
    • 3
  1. 1.Kuban State Agrarian UniversityKrasnodarRussia
  2. 2.University of Toronto at ScarboroughTorontoCanada
  3. 3.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia

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