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Condensed isoquinolines 27*. Synthesis and oxidation reactions of 5,13-dihydro-11H-isoquino[3,2-b]quinazolin-11-one

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Abstract

Condensation of 2-(cyanomethyl)benzoic acid with 2-aminobenzylamine gave 6,11-dihydro-13H-isoquino[3,2-b]quinazolin-11-one. Its oxidation in nitrobenzene led to the formation of 5,13,5′,13′-hexahydro[6,6′]bi[isoquino[3,2-b]quinazoline]-11,11′-dione, but in dichlorobenzene in the presence of elemental sulfur and iodine it gave the rearrangement product 6H-dibenzo[b,f][1,8]naphthyridin-5-one.

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Authors and Affiliations

  1. Taras Shevchenko Kiev National University, Kiev, 01033, Ukraine

    L. M. Potikha, R. M. Gutsul, A. V. Turov & V. A. Kovtunenko

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  1. L. M. Potikha
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  2. R. M. Gutsul
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  3. A. V. Turov
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  4. V. A. Kovtunenko
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Correspondence to L. M. Potikha.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No.2, 273–279, February, 2008.

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Potikha, L.M., Gutsul, R.M., Turov, A.V. et al. Condensed isoquinolines 27*. Synthesis and oxidation reactions of 5,13-dihydro-11H-isoquino[3,2-b]quinazolin-11-one. Chem Heterocycl Comp 44, 208–213 (2008). https://doi.org/10.1007/s10593-008-0024-6

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