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Chemistry of Heterocyclic Compounds

, Volume 43, Issue 11, pp 1466–1476 | Cite as

Synthesis and reactivity of 3-amino-9-methoxymethyl-7-methyl-3,4-dihydropyrido-[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones

  • E. S. KostenkoEmail author
  • M. M. Lipunov
  • E. A. Kaigorodova
  • L. D. Konyushkin
Article

Abstract

The reaction of acyl derivatives of ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate with hydrazine hydrate gives a series of tricyclic 3-amino-3,4-dihydropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones containing aliphatic, aromatic, or heteroaromatic fragments at C(2). The reactions of 3-aminopyridothieno[3,2-d]pyrimidin-4-ones with aldehydes, formamide, 2,5-dimethoxytetrahydrofuran, acetic anhydride, and Raney nickel were studied.

Keywords

3-amino-3,4-dihydropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-ones hydrazine hydrate ethyl 3-aminothienopyridinecarboxylate desulfurization Raney nickel 

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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • E. S. Kostenko
    • 1
    Email author
  • M. M. Lipunov
    • 1
  • E. A. Kaigorodova
    • 2
  • L. D. Konyushkin
    • 3
  1. 1.Kuban State Technological UniversityKrasnodarRussia
  2. 2.Kuban State Agrarian UniversityKrasnodar
  3. 3.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia

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