Chemistry of Heterocyclic Compounds

, Volume 43, Issue 11, pp 1385–1389 | Cite as

Reaction of 1,5-diaryl-3-hydroxy-4-methylsulfonyl-3-pyrrolin-2-ones with urea, hydrazine, ethylenediamine, and o-phenylenediamine

  • V. L. GeinEmail author
  • A. V. Kataeva
  • L. F. Gein


With urea 1,5-diaryl-3-hydroxy-4-methylsulfonyl-3-pyrrolin-2-ones form the 3-amino derivatives of pyrrolones. In reactions with hydrazine hydrate and ethylenediamine the corresponding salts are formed. With ethylenediamine at 180–185°C the double salt of 3-hydroxy-4-methylsulfonyl-1,5-diphenyl-3-pyrrolin-2-one forms N,N′-di(4-methylsulfonyl-1,5-diphenyl-3-pyrrolin-2-on-3-yl)-ethylenediamine. The reaction with o-phenylenediamine gives 2,3-diaryl-4-methylsulfonylpyrrolo-[2,3-b]quinoxalines.


3-amino-1,5-diaryl-4-methylsulfonyl-3-pyrrolin-2-ones 2,3-diaryl-4-methylsulfonylpyrrolo-[2,3-b]quinoxalines binucleophilic reagents 


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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  1. 1.Perm State Pharmaceutical AcademyPermRussia

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