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4-Hydroxy-2-quinolones 127. Simple method for exchanging chlorine for hydroxyl in 1-R-4-chloro-3-ethoxycarbonyl-2-oxo-1,2-dihydroquinolines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Treatment of ethyl 1-R-4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylates with sodium nitrite in DMSO is a convenient method for their conversion to the corresponding 4-hydroxy derivatives.

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Authors and Affiliations

  1. National University of Pharmacy, Kharkiv, 61002, Ukraine

    I. V. Ukrainets & N. L. Bereznyakova

  2. STC “Institute for Single Crystals”, Ukraine National Academy of Sciences, Kharkiv, 61001

    S. V. Shishkina

Authors
  1. I. V. Ukrainets
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  2. N. L. Bereznyakova
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  3. S. V. Shishkina
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Correspondence to I. V. Ukrainets.

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__________

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1359–1364, September, 2007.

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Ukrainets, I.V., Bereznyakova, N.L. & Shishkina, S.V. 4-Hydroxy-2-quinolones 127. Simple method for exchanging chlorine for hydroxyl in 1-R-4-chloro-3-ethoxycarbonyl-2-oxo-1,2-dihydroquinolines. Chem Heterocycl Comp 43, 1154–1158 (2007). https://doi.org/10.1007/s10593-007-0177-8

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  • DOI: https://doi.org/10.1007/s10593-007-0177-8

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