Skip to main content
SpringerLink
Log in

4-hydroxy-2-quinolones. 124. Synthesis and structure of ethyl 2-bromomethyl-5-oxo-1,2,6,7,8,9-hexahydro-5H-oxazolo-[3,2-a]quinoline-4-carboxylate

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The hydrogenation of the benzene part of the molecule in N-allyl-substituted 4-hydroxy-2-quinolinones does not affect the nature of their bromination by molecular bromine and gives 2-bromomethyl-5-oxo-1,2,6,7,8,9-hexahydro-5H-oxazolo[3,2-a]quinolines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. I. V. Ukrainets, E. V. Mospanova, and L. V. Sidorenko, Khim. Geterotsikl. Soedin., 1034 (2007). [Chem. Heterocycl. Comp., 43, 871 (2007)].

    Google Scholar 

  2. S. Matsumura, M. Kise, M. Ozaki, S. Tada, K. Kazuno, H. Watanabe, K. Kunimoto, and M. Tsuda, U. S. Patent 4426381 (1984). http://ep.espacenet.com.

  3. D. T. W. Chu and A. K. Claiborne, J. Heterocycl. Chem., 24, 1537 (1987).

    Article  CAS  Google Scholar 

  4. H. Kondo, M. Taguchi, Y. Inoue, F. Sakamoto, and G. Tsukamoto, J. Med. Chem., 33, 2012 (1990).

    Article  CAS  Google Scholar 

  5. I. V. Ukrainets, L. V. Sidorenko, O. V. Gorokhova, S. V. Shishkina, and A. V. Turov, Khim. Geterotsikl. Soedin., 736 (2007). [Chem. Heterocycl. Comp., 43, 617 (2007)].

    Google Scholar 

  6. I. V. Ukrainets, E. V. Kolesnik, L. V. Sidorenko, O. V. Gorokhova, and A. V. Turov, Khim. Geterotsikl. Soedin., 874 (2006). [Chem. Heterocycl. Comp., 42, 765 (2006)].

    Google Scholar 

  7. I. V. Ukrainets, L. V. Sidorenko, O. V. Gorokhova, V. B. Rybakov, V. V. Chernyshev, and O. V. Kolesnik, Visnyk Farmatsii, No. 2(38), 7 (2004).

    Google Scholar 

  8. W. L. B. Hutcheon and M. N. G. James, Acta Crystallogr., B33, 2228 (1977).

    CAS  Google Scholar 

  9. H.-B. Burgi and J. D. Dunitz, Structure Correlation, Vol. 2, VCH, Weinheim (1994), p. 741.

    Google Scholar 

  10. N. S. Zefirov, V. A. Palyulin, and E. E. Dashevskaya, J. Phys. Org. Chem., 3, 147 (1990).

    Article  CAS  Google Scholar 

  11. Yu. V. Zefirov, Kristallografiya, 42, 936 (1997).

    CAS  Google Scholar 

  12. G. M. Sheldrick, SHELXTL PLUS PC Version. A System of Computer Programs for the Determination of Crystal Structure from X ray Diffraction Data, Revision 5.1 (1998).

Download references

Author information

Authors and Affiliations

  1. National University of Pharmacy, Kharkiv, Ukraine

    I. V. Ukrainets, N. L. Bereznyakova & O. V. Gorokhova

  2. Taras Shevchenko National University, Kiev, 01033, Ukraine

    A. V. Turov

  3. STC Institute for Single Crystals, National Academy of Sciences of Ukraine, Kharkiv, 61001

    S. V. Shishkina

Authors
  1. I. V. Ukrainets
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. L. Bereznyakova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. O. V. Gorokhova
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. V. Turov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. V. Shishkina
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

__________

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1180–1188, August, 2007.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ukrainets, I.V., Bereznyakova, N.L., Gorokhova, O.V. et al. 4-hydroxy-2-quinolones. 124. Synthesis and structure of ethyl 2-bromomethyl-5-oxo-1,2,6,7,8,9-hexahydro-5H-oxazolo-[3,2-a]quinoline-4-carboxylate. Chem Heterocycl Comp 43, 1001–1007 (2007). https://doi.org/10.1007/s10593-007-0156-0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10593-007-0156-0

Keywords

Search

Navigation