Chemistry of Heterocyclic Compounds

, Volume 43, Issue 7, pp 926–935 | Cite as

Synthesis and properties of methyl hydropyrimidineacetates

  • K. Brokaite
  • V. Mickevičius
  • G. Mikulskiene


The alkylation of 1-aryl-substituted dihydro-2,4(1H,3H)-pyrimidinediones with methyl 2-bromoacetate has been studied followed by hydrolysis and condensation of the products with o-phenylenediamine. The compounds have been identified by NMR, and IR spectrometry and mass spectrometry. Structural characteristics in the 1H and 13C NMR spectra of the synthesized are discussed.


1-aryldihydro-2,4(1H,3H)-pyrimidinedione benzimidazoles hydropyrimidineacetic acids alkylation condensation NMR IR mass spectrometry 


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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • K. Brokaite
    • 1
  • V. Mickevičius
    • 1
  • G. Mikulskiene
    • 2
  1. 1.Kaunas Technological UniversityKaunasLithuania
  2. 2.Institute of BiochemistryVilniusLithuania

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