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Synthesis and properties of methyl hydropyrimidineacetates

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The alkylation of 1-aryl-substituted dihydro-2,4(1H,3H)-pyrimidinediones with methyl 2-bromoacetate has been studied followed by hydrolysis and condensation of the products with o-phenylenediamine. The compounds have been identified by NMR, and IR spectrometry and mass spectrometry. Structural characteristics in the 1H and 13C NMR spectra of the synthesized are discussed.

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Authors and Affiliations

  1. Kaunas Technological University, Kaunas, LT-50524, Lithuania

    K. Brokaite & V. Mickevičius

  2. Institute of Biochemistry, Vilnius, LT-08622, Lithuania

    G. Mikulskiene

Authors
  1. K. Brokaite
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  2. V. Mickevičius
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  3. G. Mikulskiene
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, 1095–1105, July, 2007.

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Brokaite, K., Mickevičius, V. & Mikulskiene, G. Synthesis and properties of methyl hydropyrimidineacetates. Chem Heterocycl Compd 43, 926–935 (2007). https://doi.org/10.1007/s10593-007-0146-2

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  • DOI: https://doi.org/10.1007/s10593-007-0146-2

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