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4-Hydroxy-2-quinolones 123. Amidation of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]-quinoline-4-carboxylic acid

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carboxylic acid with thionyl chloride is accompanied by a transformation of the oxazoloquinolone ring to give 4-chloro-1-(2,3-dichloropropyl)-2-oxo-1,2-dihydroquinoline-3-carboxylic acid chloride.

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References

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1034–1042, July, 2007.

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Ukrainets, I.V., Bereznyakova, N.L., Turov, A.V. et al. 4-Hydroxy-2-quinolones 123. Amidation of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]-quinoline-4-carboxylic acid. Chem Heterocycl Compd 43, 871–878 (2007). https://doi.org/10.1007/s10593-007-0138-2

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  • DOI: https://doi.org/10.1007/s10593-007-0138-2

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