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Chemistry of Heterocyclic Compounds

, Volume 43, Issue 7, pp 871–878 | Cite as

4-Hydroxy-2-quinolones 123. Amidation of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]-quinoline-4-carboxylic acid

  • I. V. Ukrainets
  • N. L. Bereznyakova
  • A. V. Turov
  • S. V. Shishkina
Article

Abstract

The reaction of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carboxylic acid with thionyl chloride is accompanied by a transformation of the oxazoloquinolone ring to give 4-chloro-1-(2,3-dichloropropyl)-2-oxo-1,2-dihydroquinoline-3-carboxylic acid chloride.

Keywords

oxazolo[3,2-a]quinoline 4-chloro-2-quinolinone amidation ring closing X-ray analysis 

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References

  1. 1.
    I. V. Ukrainets, E. V. Mospanova, and L. V. Sidorenko, Khim. Geterotsikl. Soedin., 1023 (2007). [Chem. Heterocycl. Comp., 43, 863 (2007)].Google Scholar
  2. 2.
    Yu. V. Zefirov, Kristallografiya, 42, 936 (1997).Google Scholar
  3. 3.
    I. V. Ukrainets, L. V. Sidorenko, O. V. Gorokhova, S. V. Shishkina, and A. V. Turov, Khim. Geterotsikl. Soedin., 736 (2007). [Chem. Heterocycl. Comp., 43, 617 (2007)].Google Scholar
  4. 4.
    G. M. Sheldrick, SHELXTL PLUS PC Version. A System of Computer Programs for the Determination of Crystal Structure from X-ray Diffraction Data, Revision 5.1 (1998).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • I. V. Ukrainets
    • 1
  • N. L. Bereznyakova
    • 1
  • A. V. Turov
    • 2
  • S. V. Shishkina
    • 3
  1. 1.National University of PharmacyKharkivUkraine
  2. 2.Taras Shevchenko National UniversityKievUkraine
  3. 3.STC Institute for Single CrystalsNational Academy of SciencesKharkivUkraine

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