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Chemistry of Heterocyclic Compounds

, Volume 43, Issue 7, pp 863–870 | Cite as

4-Hydroxy-2-quinolones. 122. 1-Hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]-quinoline-2-carboxylic acid hetarylamides as potential antitubercular agents

  • I. V. Ukrainets
  • E. V. Mospanova
  • L. V. Sidorenko
Article

Abstract

An improved method is reported for the synthesis of a series of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid hetarylamides. The antitubercular activity of all of the compounds prepared has been studied. The structure-biological activity dependence revealed is discussed.

Keywords

hetarylamides 4-hydroxy-2-oxoquinoline-3-carboxylic acids amidation antitubercular activity 

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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • I. V. Ukrainets
    • 1
  • E. V. Mospanova
    • 1
  • L. V. Sidorenko
    • 1
  1. 1.National University of PharmacyKharkivUkraine

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