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Preparation of 4-(azol-1-yl)butyric acids by the interaction of azoles with γ-butyrolactone

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The interaction of salts of imidazole, 1,2,4-triazole, benzimidazole, and 2-benzylbenzimidazole with γ-butyrolactone has been studied. Ab initio quantum-chemical calculations showed a preference for N-alkylation on interaction of azolates with γ-butyrolactone.

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Authors and Affiliations

  1. D. Mendeleyev University of Chemical Technology of Russia, Moscow, 125047, Russia

    A. L. Alekseenko & S. V. Popkov

Authors
  1. A. L. Alekseenko
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  2. S. V. Popkov
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Correspondence to S. V. Popkov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6. pp. 910–916, June, 2007.

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Alekseenko, A.L., Popkov, S.V. Preparation of 4-(azol-1-yl)butyric acids by the interaction of azoles with γ-butyrolactone. Chem Heterocycl Compd 43, 769–775 (2007). https://doi.org/10.1007/s10593-007-0124-8

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  • DOI: https://doi.org/10.1007/s10593-007-0124-8

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