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Studies on quinazoline chemistry. 4. Unexpected route of acylation of alkyl 2-(4,4-diphenyl-1,2,3,4-tetrahydro-2-quinazolinylidene)acetates. Molecular structure of methyl 2-(4,4-diphenyl)-1,2,3,4-tetrahydro-2-quinazolinylidene)-3-oxobutanoate

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A study of the reaction of quinazoline derivatives with acid chlorides in the absence of acids has shown that alkyl 2-(4,4-diphenyl-1,2,3,4-tetrahydro-2-quinazolinylidene)acetates undergo C-acylation. The molecular structure of methyl 2-(4,4-diphenyl-1,2,3,4-tetrahydro-2-quinazolinylidene)-3-oxobutanoate has been investigated by X-ray analysis.

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Authors and Affiliations

  1. Kuban State Technological University, Krasnodar, 350072, Russia

    E. V. Gromachevskaya, E. A. Kaigorodova, V. E. Zavodnik & G. D. Krapivin

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  1. E. V. Gromachevskaya
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  2. E. A. Kaigorodova
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  3. V. E. Zavodnik
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  4. G. D. Krapivin
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Correspondence to E. V. Gromachevskaya.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 886–983, June, 2007.

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Gromachevskaya, E.V., Kaigorodova, E.A., Zavodnik, V.E. et al. Studies on quinazoline chemistry. 4. Unexpected route of acylation of alkyl 2-(4,4-diphenyl-1,2,3,4-tetrahydro-2-quinazolinylidene)acetates. Molecular structure of methyl 2-(4,4-diphenyl)-1,2,3,4-tetrahydro-2-quinazolinylidene)-3-oxobutanoate. Chem Heterocycl Compd 43, 748–754 (2007). https://doi.org/10.1007/s10593-007-0121-y

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  • DOI: https://doi.org/10.1007/s10593-007-0121-y

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