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4-Hydroxy-2-quinolones 119. Reaction of ethyl 1-R-4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate with malononitrile

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

In acid medium ethyl 1-R-4-dicyanomethyl-2-oxo-1,2-dihydroquinoline-3-carboxylates are hydrated in the ketenimine tautomer form exclusively to the corresponding quinolylcyanoacetamides.

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References

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Authors and Affiliations

  1. National University of Pharmacy, Kharkiv, 61002, Ukraine

    I. V. Ukrainets, N. L. Bereznyakova & V. A. Parshikov

  2. NTC Institute for Single Crystals, National Academy of Sciences, Kharkov, 61001

    S. V. Shishkina

Authors
  1. I. V. Ukrainets
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  2. N. L. Bereznyakova
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  3. V. A. Parshikov
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  4. S. V. Shishkina
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Correspondence to I. V. Ukrainets.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 856–863, June, 2007.

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Ukrainets, I.V., Bereznyakova, N.L., Parshikov, V.A. et al. 4-Hydroxy-2-quinolones 119. Reaction of ethyl 1-R-4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate with malononitrile. Chem Heterocycl Compd 43, 722–728 (2007). https://doi.org/10.1007/s10593-007-0118-6

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  • DOI: https://doi.org/10.1007/s10593-007-0118-6

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