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Interaction of aminoazoles with Meldrum’s acid and dialkyl ketones or cyclohexanone

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Interaction of 3-amino-5-methylpyrazole, 3-amino-5-methylthio-, and 3,5-diamino-1,2,4-triazole with Meldrum’s acid, acetone, ethyl methyl ketone, and cyclohexanone leads to alkyl-substituted pyrazolo[3,4-b]pyridin-6-ones and 1,2,4-triazolo[1,5-a]pyrimidin-7-ones respectively. The structure of 5,5-dimethyl-2-methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-7-one was demonstrated by an X-ray structural investigation.

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References

  1. Bang-Chi Chen, Heterocycles, 32, 529 (1991).

    Article  CAS  Google Scholar 

  2. J. Quiroga, A. Hormaza, B. Insuasti, C. Saitz, C. Jullian, and A. Canete, J. Heterocycl. Chem., 35, 61 (1998).

    CAS  Google Scholar 

  3. D. Clarke, R. Mares, and H. McNab, J. Chem. Soc., Perkin Trans. 1, 12, 1799 (1997).

    Article  Google Scholar 

  4. V. V. Lipson, V. D. Orlov, S. M. Desenko, T. M. Karnozhitskaya, and M. G. Shirobokova, Khim. Geterotsikl. Soedin., 664 (1999). [Chem. Heterocycl. Comp., 35, 595 (1999)].

    Google Scholar 

  5. V. V. Lipson, V. D. Orlov, S. M. Desenko, S. V. Shishkina, O. V. Shishkin, and M. G. Shirobokova, Khim. Geterotsikl. Soedin., 1190 (2000). [Chem. Heterocycl. Comp., 36, 1039 (2000)].

    Google Scholar 

  6. H. McNab, Chem. Soc. Rev., 7, 375 (1978).

    Article  Google Scholar 

  7. V. M. Chernyshev, N. D. Zemlyakov, and V. A. Taranushich, Russian Patent 2148579, www.fips.ru.

  8. M. A. E. Shaban and A. E. A. Morgaan, Adv. Heterocycl. Chem., 73, 131 (1999).

    Article  CAS  Google Scholar 

  9. N. S. Zefirov, V. A. Palyulin, and E. E. Dashevskaya, J. Phys. Org. Chem., 3, 147 (1990).

    Article  CAS  Google Scholar 

  10. H.-B. Burgi and J. D. Dunitz, in Structure Correlations, Vol. 2, VCH, Weinheim (1994), p. 741.

    Google Scholar 

  11. G. M. Sheldrick, SHELXTL PLUS. PC Version. A System of Computer Programs for the Determination of Crystal Structure from X-ray Diffraction Data, rev. 5.1, Siemens Analytical X-ray Instruments Inc., Germany, 1998.

    Google Scholar 

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Authors and Affiliations

  1. V. Ya. Danilevsky Institute of Endocrine Pathology Problems, Academy of Medical Sciences of Ukraine, Kharkiv, 61002

    V. V. Lipson, V. V. Borodina & M. G. Shirobokova

  2. Institute of Single Crystals, National Academy of Sciences of Ukraine, Kharkiv, 61001

    S. M. Desenko, O. V. Shishkin & R. I. Zubatyuk

Authors
  1. V. V. Lipson
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  2. V. V. Borodina
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  3. M. G. Shirobokova
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  4. S. M. Desenko
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  5. O. V. Shishkin
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  6. R. I. Zubatyuk
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 595–601, April, 2007.

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Lipson, V.V., Borodina, V.V., Shirobokova, M.G. et al. Interaction of aminoazoles with Meldrum’s acid and dialkyl ketones or cyclohexanone. Chem Heterocycl Compd 43, 490–495 (2007). https://doi.org/10.1007/s10593-007-0071-4

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  • DOI: https://doi.org/10.1007/s10593-007-0071-4

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