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New functionalized pyrazolines from 1-aroyl-2-phenylacetylenes and thiocarbonohydrazides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 1-aroyl-2-phenylacetylenes with thiocarbonohydrazide and benzaldehyde thiocarbohydrazone in acetic acid-water or ethanol-water systems with the reagents in an equimolar ratio leads to the selective formation of 1-carbothiohydrazinoyl-5-hydroxy-3-phenyl-5-R-2-pyrazolines. Ring-chain tautomerism involving the enamine and hydrazone forms was detected for solutions of the pyrazolines (with R = 2-thienyl) in DMSO.

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Authors and Affiliations

  1. A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Irkutsk

    M. Yu. Dvorko, A. I. Albanov, N. N. Chipanina, L. V. Sherstyannikova, V. G. Samoilov, T. N. Komarova & T. E. Glotova

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  1. M. Yu. Dvorko
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  2. A. I. Albanov
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  3. N. N. Chipanina
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  4. L. V. Sherstyannikova
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  5. V. G. Samoilov
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  6. T. N. Komarova
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  7. T. E. Glotova
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Additional information

Dedicated to Academician M. G. Voronkov on his 85th birthday.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1655–1661, November, 2006.

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Dvorko, M.Y., Albanov, A.I., Chipanina, N.N. et al. New functionalized pyrazolines from 1-aroyl-2-phenylacetylenes and thiocarbonohydrazides. Chem Heterocycl Compd 42, 1421–1426 (2006). https://doi.org/10.1007/s10593-006-0258-0

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  • DOI: https://doi.org/10.1007/s10593-006-0258-0

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