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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 7, pp 897–900 | Cite as

Synthesis of substituted 2-amino-5,6-dihydropyrimidin-4-ones using an aza-Wittig reaction

  • V. S. Kochubey
  • Ya. S. Blochin
  • O. G. Rodin
  • V. P. Perevalov
Article

Abstract

An aza-Wittig reaction has been used for the first time in the synthesis of substituted 2-amino-5,6-dihydropyrimidin-4-ones via condensation of triphenyliminophosphoranes with aromatic heterocumulenes (arylisocyanates and thiocyanates).

Keywords

2-amino-5,6-dihydropyrimidin-4-ones N-arylcarbodiimides heterocumulenes triphenyliminophosphoranes aza-Wittig reaction 

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References

  1. 1.
    H. Wamhoff, G. Richard, and S. Stölben, Adv. Heterocycl. Chem., 64, 159 (1995).CrossRefGoogle Scholar
  2. 2.
    H. Wamhoff, H. Wintersohl, S. Stölben, J. Paasch, Z. Nai-jue, and G. Fang, Liebigs Ann. Chem., 901 (1990).Google Scholar
  3. 3.
    H. Wamhoff and J. Paasch, Liebigs Ann. Chem., 995 (1990).Google Scholar
  4. 4.
    H. Wamhoff, E. Kroth, and C. Strauch, Synthesis, 1129 (1993).Google Scholar
  5. 5.
    H. Staudinger and J. Meyer, Helv. Chim. Acta, 2, 635 (1919).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • V. S. Kochubey
    • 1
  • Ya. S. Blochin
    • 1
  • O. G. Rodin
    • 1
  • V. P. Perevalov
    • 1
  1. 1.ASINEX Ltd.MoscowRussia

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