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Selective hydrogenolysis of benzyl-protected 1-hydroxy-3-hydroxyimino-2-pyrrolidinones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

On hydrogenolysis of 1-benzyloxy-3-benzyloxyimino-2-pyrrolidinones in the presence of 10% Pd/C selective removal occurs of the O-benzyl (Bn) protection of the hydroxamic acid, with retention of the double bond and benzyl protection of the oxime group. The yields of reaction products were 66–98%.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, Riga, LV-1006

    M. Katkevichs, E. Korchagova, T. Ivanova, V. Slavinska & E. Lukevics

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  1. M. Katkevichs
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  2. E. Korchagova
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  3. T. Ivanova
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  4. V. Slavinska
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  5. E. Lukevics
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1011–1014, July, 2006.

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Katkevichs, M., Korchagova, E., Ivanova, T. et al. Selective hydrogenolysis of benzyl-protected 1-hydroxy-3-hydroxyimino-2-pyrrolidinones. Chem Heterocycl Compd 42, 872–874 (2006). https://doi.org/10.1007/s10593-006-0172-5

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  • DOI: https://doi.org/10.1007/s10593-006-0172-5

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