Chemistry of Heterocyclic Compounds

, Volume 42, Issue 7, pp 868–871 | Cite as

Reductive deacetylation of 3,3,3-trifluoro-1-(2-thenoyl)acetone

  • N. V. Russavskaya
  • V. A. Grabel’nyh
  • E. N. Deryagina
  • N. A. Korchevin


The reaction of 3,3,3-trifluoro-1-(2-thenoyl)acetone with sulfur—hydrazine hydrate—alkali and hydrazine hydrate—alkali systems is effected by reductive fission of the trifluoroacetyl group and leads to the formation of nitrogen-containing derivatives of 2-acetylthiophene. Sodium polysulfide assists the reductive fission of 3,3,3-trifluoro-1-(2-thenoyl)acetone.


hydrazine polysulfide anions 3,3,3-trifluoro-1-(2-thenoyl)acetone deacetylation 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • N. V. Russavskaya
    • 1
  • V. A. Grabel’nyh
    • 1
  • E. N. Deryagina
    • 1
  • N. A. Korchevin
    • 1
  1. 1.Irkutsk A. E. Favorsky Institute of ChemistrySiberian Branch of the Russian Academy of SciencesIrkutsk

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