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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 6, pp 798–802 | Cite as

Synthesis of 4-aryl-1,3-diphenyl-1,4,5,10-tetrahydropyrazolo-[3,4-b][1,5]benzodiazepines

  • I. B. Dzvinchuk
  • A. V. Turov
  • M. O. Lozinskii
Article

Abstract

A convenient method is proposed for the synthesis of the previously unknown 4-aryl-1,3-diphenyl-1,4,5,10-tetrahydropyrazolo[3,4-b][1,5]benzodiazepines by cyclocondensation of 5-(2-aminoanilino)-1,3-diphenylpyrazole with aromatic aldehydes. The reaction only takes place very selectively with aldehydes which contain electron acceptor substituents in the aryl fragment.

Keywords

aldehydes 1,5-benzodiazepines pyrazoles structure cyclocondensation 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • I. B. Dzvinchuk
    • 1
  • A. V. Turov
    • 2
  • M. O. Lozinskii
    • 1
  1. 1.Institute of Organic ChemistryUkraine National Academy of SciencesKiev
  2. 2.Taras Shevchenko National UniversityKievUkraine

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