Cyclization products of N-fluorophenyl-β-alanines and their properties
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Interaction of 2-and 4-fluorophenylamines with acrylic and itaconic acids leads to the synthesis of the corresponding N-substituted β-alanines, the cyclization of which leads to derivatives of dihydropyrimidinone, 4-carboxy-2-pyrrolidinone, and tetrahydropyridone. Compounds having benzimidazole, pyrazole, and hydrazine fragments in the molecule have been obtained from 4-carboxy-1-(4-fluorophenyl)-2-pyrrolidinone.
Keywordsdihydropyrimidinones N-substituted β-alanines 4-carboxy-2-pyrrolidinones tetrahydropyridone condensation
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