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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 5, pp 594–599 | Cite as

Novel synthesis of 2-amino-3-hetaryl-4(5H)-oxothiophenes

  • Yu. M. Volovenko
  • T. A. Volovnenko
  • A. V. Dobrydnev
Article

Abstract

3-Cyano-3-hetaryl-2-oxopropyl thioacetates were obtained by the acylation of hetarylacetonitriles with acetylmercaptoacetyl chloride. Their reaction with amines led to the formation of 2-amino-3-hetaryl-4(H)-oxothiophenes.

Keywords

acetylmercaptoacetyl chloride 2-amino-3-hetaryl-4(5H)-oxothiophenes 3-cyano-3-hetaryl-2-oxopropylethanethioates hetarylacetonitriles 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Yu. M. Volovenko
    • 1
  • T. A. Volovnenko
    • 1
  • A. V. Dobrydnev
    • 1
  1. 1.Taras Shevchenko Kiev National UniversityKievUkraine

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