Abstract
N-Substituted 5-pryazolones undergo thermal condensation with esters of β-keto acids, losing water and alcohol molecules, to form N-substituted pyrano[2,3-c]pyrazol-6-ones. The pyran ring in these products is readily cleaved by the action of alkali to give the corresponding salts of unsaturated acids.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 367–372, March, 2006.
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Nam, N.L., Grandberg, I.I. Condensation of N-3-substituted 5-pyrazolones with esters of β-keto acids. Synthesis of pyrano[2,3-c]pyrazol-6-ones. Chem Heterocycl Compd 42, 326–330 (2006). https://doi.org/10.1007/s10593-006-0089-z
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DOI: https://doi.org/10.1007/s10593-006-0089-z