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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 3, pp 285–319 | Cite as

Synthesis of heterocycles with polyfluoroalkyl substituents from unsaturated compounds containing polyfluoroalkyl groups. (Review)

  • G. G. Furin
Article

Abstract

Methods for the construction of heterocyclic systems containing polyfluoroalkyl substituents from derivatives of ethylene and acetylene are discussed. It is shown that various compounds with polyfluoroalkyl groups can be used as building blocks: α,β-unsaturated carbonyl compounds, their synthetic organosilicon equivalents (silyl-substituted alcohols, silyl ethers of enols), and also sulfones, nitriles, polyfluoroalkenes (in reactions at the double bond), acetylenecarboxylic acids, their esters, and polyfluoroalkynes.

Keywords

unsaturated compounds with a polyfluoralkyl group polyfluoroalkyl-substituted heterocycles dipolar cycloaddition nucleophilic intramolecular cyclization nucleophilic addition 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • G. G. Furin
    • 1
  1. 1.N. N. Vorozhtsov Novosibirsk Institute of Organic ChemistrySiberian Branch of the Russian Academy of SciencesNovosibirsk

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