Chemistry of Heterocyclic Compounds

, Volume 42, Issue 2, pp 197–199 | Cite as

Investigations on 2,3′-biquinoline series. 19. Regioselectivity of the reaction of 1,1′-dialkyl-3,3′-di(2-quinolyl)-1,1′,4,4′-tetrahydro-4,4′-biquinolines with organomagnesium and organolithium compounds

  • O. A. Antonova
  • V. I. Goncharov
  • A. V. Aksenov


1,1′-Dialkyl-3,3′-di(2-quinolyl)-1,1′,4,4′-tetrahydro-4,4′-biquinolines react with organolithium and organo-magnesium compounds to form 1′-alkyl-2′-R-1′,2′-dihydro-2,3′-biquinolines.


1,1′-dialkyl-3,3′-di(2-quinolyl)-1,1′,4,4′-tetrahydro-4,4′-biquinolines 1′,2′-dihydro-2,3′-biquinolines organolithium compounds nucleophilic substitution Grignard reagents 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • O. A. Antonova
    • 1
  • V. I. Goncharov
    • 1
  • A. V. Aksenov
    • 2
  1. 1.Stavropol State Medical AcademyStavropolRussia
  2. 2.Stavropol State UniversityStavropolRussia

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