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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 1, pp 109–114 | Cite as

Syntheses based on 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones

  • T. V. Kochikyan
  • E. V. Harutyunyan
  • V. S. Harutyunyan
  • A. A. Avetisyan
Article

Abstract

By reaction of 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones with thiourea and substituted thioureas under Hansch reaction conditions, we have obtained the novel heterocycles 3-[2′-amino(arylamino)thiazol-4-yl]-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones. By reacting the above-indicated bromoacetyl spirodilactones with 5-aryl-3-mercapto-1,2,4-triazoles, we obtained 8-substituted 3-(aryl-3,8-dimethyl-1′,2′,4′-triazol-3′-yl)thioacetyl-2,7-dioxaspiro[4,4]nonane-1,6-diones.

Keywords

aminothiazoles bromoacetyl lactones spirodibutanolides triazoles 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • T. V. Kochikyan
    • 1
  • E. V. Harutyunyan
    • 1
  • V. S. Harutyunyan
    • 1
  • A. A. Avetisyan
    • 1
  1. 1.Chemistry DepartmentYerevan State UniversityYerevanRepublic of Armenia

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