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Chemistry of Heterocyclic Compounds

, Volume 42, Issue 1, pp 60–63 | Cite as

Investigations on 2,3′-biquinolines. 18. New convenient one-pot synthesis of 1′-alkyl-1′,4′-dihydro-2,3′-biquinolyl-4′-thiones and their conversion into 1′-alkyl-1′,4′-dihydro-2,3′-biquinolyl-4′-ones

  • D. V. Moiseev
  • N. V. Demidova
  • V. I. Goncharov
  • A. V. Aksenov
Article

Abstract

A method has been developed for the one pot synthesis of 1′-alkyl-1′,4′-dihydro-2.3′-biquinolyl-4′-thiones based on the reduction of 1-alkyl-3-(2-quinolyl)quinolinium halides with sodium borohydride and subsequent thiolation. 1′-Alkyl-1′,4′-dihydro-2,3′-biquinolyl-4′-ones were obtained in close to quantitative yield by the oxidation of 1′-alkyl-1′, 4′-dihydro-2,3′-biquinolyl-4′-thiones.

Keywords

1′-alkyl-1′,4′-dihydro-2,3′-biquinolyl-4′-ones 1′-alkyl-1′,4′-dihydro-2,3′-biquinolyl-4′-thiones sodium borohydride 1-alkyl-3-(2-quinolyl)-quinolinium halides 1′,4′-dihydro-2,3′-biquinolines sulfur oxidation thiolation 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • D. V. Moiseev
    • 1
  • N. V. Demidova
    • 1
  • V. I. Goncharov
    • 2
  • A. V. Aksenov
    • 1
  1. 1.Stavropol State UniversityStavropolRussia
  2. 2.Stavropol State Medical AcademyStavropolRussia

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