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Synthesis of 1-Acyl-5-amino-4-ethoxycarbonylpyrazoles from Monohydrazides of Cyclohexenedicarboxylic Acids and Ethyl Ethoxymethylenecyanoacetate

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Heating monohydrazides of cyclohexenedicarboxylic acids with ethyl ethoxymethylenecyanoacetate at reflux gives the corresponding N-substituted hydrazides. This reaction carried out in pyridine gives 1-acyl-5-amino-4-ethoxycarbonylpyrazoles.

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Authors and Affiliations

  1. Riga Technical University, LV-1048, Riga, Latvia

    D. Zicane, Z. Tetere, I. Ravina & M. Petrova

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  1. D. Zicane
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  2. Z. Tetere
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  3. I. Ravina
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  4. M. Petrova
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1332–1335, September, 2005.

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Zicane, D., Tetere, Z., Ravina, I. et al. Synthesis of 1-Acyl-5-amino-4-ethoxycarbonylpyrazoles from Monohydrazides of Cyclohexenedicarboxylic Acids and Ethyl Ethoxymethylenecyanoacetate. Chem Heterocycl Compd 41, 1130–1133 (2005). https://doi.org/10.1007/s10593-005-0291-4

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  • DOI: https://doi.org/10.1007/s10593-005-0291-4

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