Abstract
The interaction of anions, obtained by treating 2,4,5-trimethylthiazole and 2,5-dimethyl-4-phenylthiazole with butyllithium, with aliphatic and aromatic aldehydes leads to substituted 2-thiazolyl-1-ethanols. It was established that the metallation reaction occurs at the 2-methyl group of the thiazoles.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1038–1043, July, 2005.
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Liakina, A.Y., Formanovsky, A.A., Popova, I.S. et al. Use of a Metallation Reaction to Obtain Substituted 2-(5-Methyl-2-thiazolyl)ethanols. Chem Heterocycl Compd 41, 877–882 (2005). https://doi.org/10.1007/s10593-005-0242-0
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DOI: https://doi.org/10.1007/s10593-005-0242-0