Abstract
Substituted hexahydroindazoles were obtained by the reaction of 6-arylidene-2-furfurylidene-cyclohexanones with phenylhydrazine. It was concluded by means of the NMR spectra that azacyclization takes place regioselectively with participation of the arylidenecyclohexanone fragment.
Similar content being viewed by others
REFERENCES
J. Krapcho and C. F. Turk, US Pat. 3957762 (1976); Ref. Zh. Khim., 2O118P (1977).
J. Krapcho and C. F. Turk, Socialist Federative Republic of Yugoslavia Pat. 32167 (1983); Ref. Zh. Khim., 12O148P (1986).
J. Krapcho and C. F. Turk, J. Med. Chem., 22, 207 (1979).
G. C. Rovnyak, US Pat. 4178379 (1979); Ref. Zh. Khim., 12O111P (1980).
G. C. Rovnyak, R. C. Millonig, J. Schwartz, and V. Shu, J. Med. Chem., 25, 1482 (1982).
T. Lorand, B. Kocsis, and P. Sohar, Eur. J. Med. Chem., 34, 1009 (1999).
T. Lorand and D. Szabo, Acta Chim. Acad. Sci. Hung., 86, 449 (1975).
R. A. Kabli, A. M. Kaddah, A. M. Khali, and A. A. Khalaf, Indian J. Chem., 25, 152 (1986).
S. Gupta and S. N. Rastogi, Indian J. Chem., Sect. B, 34B, 245 (1995).
V. Vijayabaskar, S. Perumal, S. Selvaray, and M. J. E. Hewlins, Magn. Reson. Chem., 37, 65 (1999).
C. Qi and X. Wang, Beijing Shifan Daxue Xuebao, Ziran Kexueban, 32, 524 (1996); Chem. Abstr., 81393 (1997).
G. C. Rovnyak and V. Shu, J. Org. Chem., 44, 2518 (1979).
A. P. Kriven'ko, A. A. Bugaev, and A. G. Golikov, Khim. Geterotsikl. Soedin., 191 (2005).
M. S. Puar, G. C. Rovnyak, A. I. Cohen, and B. Toeplitz, J. Org. Chem., 44, 2513 (1979).
Author information
Authors and Affiliations
Additional information
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 986–990, July, 2005.
Rights and permissions
About this article
Cite this article
Bugaev, A.A., Golikov, A.G. & Kriven'ko, A.P. Synthesis of Substituted Hexahydroindazoles. Chem Heterocycl Compd 41, 831–834 (2005). https://doi.org/10.1007/s10593-005-0233-1
Received:
Issue Date:
DOI: https://doi.org/10.1007/s10593-005-0233-1