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Nitropyridines. 2. Hantzsch Synthesis of Nitro- and Dinitropyridines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The interaction of α, β-unsaturated nitro ketones and various enamines leads to the synthesis of 5-nitro-1,4-dihydropyridines containing acetyl, amide, benzoyl, ester, and cyano groups in position 3, and also unsymmetrical 3,5-dinitro-1,4-dihydropyridines. Aromatization of the nitrodihydropyridines was carried out with sodium nitrite in acetic acid.

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Authors and Affiliations

  1. Department of Organic Chemistry, Omsk State University, Omsk, 644077, Russia

    G. P. Sagitullina, L. V. Glizdinskaya & R. S. Sagitullin

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  1. G. P. Sagitullina
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  2. L. V. Glizdinskaya
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  3. R. S. Sagitullin
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 858–863, June, 2005.

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Sagitullina, G.P., Glizdinskaya, L.V. & Sagitullin, R.S. Nitropyridines. 2. Hantzsch Synthesis of Nitro- and Dinitropyridines. Chem Heterocycl Compd 41, 739–744 (2005). https://doi.org/10.1007/s10593-005-0214-4

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  • DOI: https://doi.org/10.1007/s10593-005-0214-4

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