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Addition of Nitrile Oxides to N-Allylsaccharin

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The addition of nitrile oxides to N-allylsaccharin has been studied and it has been shown that the reaction occurs regiospecifically to form a 5-substituted isomer. The molecular structure of 2-{ 5-[(3-methyl)isoxazolin-2-yl]methyl}-3-oxo-2,3-dihydrobenz[d]isothiazole 1,1-dioxide has been determined by X-ray analysis. A feature of the crystal of this compound is the presence of a supersymmetrical crystalline structure with two independent molecules associated by a center of pseudoinversion.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, Riga, LV-1006, Latvia

    V. Dirnens, S. Belyakov & E. Lukevics

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  1. V. Dirnens
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  2. S. Belyakov
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  3. E. Lukevics
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Dedicated to Professor V. I. Minkin on the occasion of his anniversary

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 450–456, March, 2005.

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Dirnens, V., Belyakov, S. & Lukevics, E. Addition of Nitrile Oxides to N-Allylsaccharin. Chem Heterocycl Compd 41, 393–399 (2005). https://doi.org/10.1007/s10593-005-0160-1

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  • DOI: https://doi.org/10.1007/s10593-005-0160-1

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