Chemistry of Heterocyclic Compounds

, Volume 41, Issue 3, pp 329–339 | Cite as

Synthesis and Investigation of the Conformational Mobility of Certain (N-Benzyl-N-Nitrosoamino)azoles

  • O. V. Dyablo
  • A. V. Mikhailus
  • A. F. Pozharskii
  • D. S. Trishkin


The N-benzyl-N-nitroso derivatives of 1- and 4-amino-1,2,4-triazoles, and 2-amino-5-phenyltetrazoles, 1-aminobenzotriazole, 7-amino-8-methyltheophylline, and 1-amino-3-methylbenzimidazol-2-one have been synthesized. The ratio of E- and Z-forms for them, arising as a result of hindered rotation about the N-N(O) bond, has been determined by 1H NMR spectroscopy. The energy of activation for the E↔Z transition was estimated in several cases.


N-nitrosoamines conformation nitrosation temperature-dependent 1H NMR spectrum 


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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • O. V. Dyablo
    • 1
  • A. V. Mikhailus
    • 1
  • A. F. Pozharskii
    • 1
  • D. S. Trishkin
    • 1
  1. 1.Rostov State UniversityRostov-on-DonRussia

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