Abstract
The cyclocondensation of methylcinnamates and arylidene derivatives of Meldrum’s acid with 3-amino-5-methylthio-1,2,4-triazole in DMF gives 2-methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]-pyrimidin-5-ones. The reaction involving arylidene derivatives of Meldrum’s acid or its synthetic equivalents in ethyl acetate with a catalytic amount of pyridine gives a mixture of 2-methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-5- and -7-ones.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 246–251, February, 2005.
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Lipson, V.V., Desenko, S.M., Borodina, V.V. et al. 2-Methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-5- and -7-Ones. Chem Heterocycl Compd 41, 216–220 (2005). https://doi.org/10.1007/s10593-005-0130-7
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DOI: https://doi.org/10.1007/s10593-005-0130-7